Bos taurus Gene: SLC5A1
Summary
InnateDB Gene IDBG-636848.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC5A1
Gene Name sodium/glucose cotransporter 1
Synonyms SGLT1
Species Bos taurus
Ensembl Gene ENSBTAG00000012851
Encoded Proteins
sodium/glucose cotransporter 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000100170:
This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:72690558-72740066
Strand Forward strand
Band
Transcripts
ENSBTAT00000017073 ENSBTAP00000017073
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0005355 glucose transmembrane transporter activity
GO:0005412 glucose:sodium symporter activity
GO:0005515 protein binding
Biological Process
GO:0006810 transport
GO:0015758 glucose transport
GO:0050892 intestinal absorption
GO:0055085 transmembrane transport
Cellular Component
GO:0005903 brush border
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Inositol transporters pathway
Na+-dependent glucose transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Hexose transport pathway
Transmembrane transport of small molecules pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Orphan transporters pathway
Metabolism pathway
SLC-mediated transmembrane transport pathway
Disease pathway
Glycogen storage diseases pathway
KEGG
Bile secretion pathway
Carbohydrate digestion and absorption pathway
Carbohydrate digestion and absorption pathway
Bile secretion pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A5HNF2 F1MD24 Q9TTR6
UniProt Splice Variant
Entrez Gene 282361
UniGene Bt.92569
RefSeq NM_174606 XM_005218130 XM_005218131
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AJ250368 DAAA02045649 DAAA02045650 DAAA02045651 EF544430
GenPept ABQ12424 CAB58424
RNA Seq Atlas 282361