InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Rdh12

Summary

InnateDB Gene

IDBG-152851.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rdh12

Gene Name

retinol dehydrogenase 12

Synonyms

A930033N07Rik

Species

Mus musculus

Ensembl Gene

ENSMUSG00000021123

Encoded Proteins

IDBP-152853

retinol dehydrogenase 12

IDBP-401423

retinol dehydrogenase 12

IDBP-539528

retinol dehydrogenase 12

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000139988:
The protein encoded by this gene is an NADPH-dependent retinal reductase whose highest activity is toward 9-cis and all-trans-retinol. The encoded enzyme also plays a role in the metabolism of short-chain aldehydes but does not exhibit steroid dehydrogenase activity. Defects in this gene are a cause of Leber congenital amaurosis type 3 (LCA3). [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 12:79208914-79222665

Strand

Forward strand

Band

Transcripts

ENSMUST00000021548	ENSMUSP00000021548
ENSMUST00000122227	ENSMUSP00000112543
ENSMUST00000151980
ENSMUST00000140823	ENSMUSP00000118851

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004745	retinol dehydrogenase activity
GO:0005515	protein binding
GO:0016491	oxidoreductase activity
GO:0050662	coenzyme binding

Biological Process

GO:0007601	visual perception
GO:0008152	metabolic process
GO:0042572	retinol metabolic process
GO:0044237	cellular metabolic process
GO:0050896	response to stimulus
GO:0055114	oxidation-reduction process