Version 5.4
| Mus musculus Gene: Pla2g12b | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-153813.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Pla2g12b | ||||||||
| Gene Name | phospholipase A2, group XIIB | ||||||||
| Synonyms | 2010002E04Rik; hlb218; Pla2g13 | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Gene | ENSMUSG00000009646 | ||||||||
| Encoded Proteins |
phospholipase A2, group XIIB
phospholipase A2, group XIIB
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138308:
Phospholipase A2 (PLA2) enzymes catalyze hydrolysis of glycolipids to release free fatty acids and lysophospholipids. PLA2G12B belongs to the PLA2 family, but it is catalytically inactive due to an amino acid change in its active site and has altered phospholipid-binding properties (Rouault et al., 2003 [PubMed 14516201]).[supplied by OMIM, Mar 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 10:59403660-59421976 | ||||||||
| Strand | Forward strand | ||||||||
| Band | B4 | ||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
Glycerophospholipid metabolism pathway
Arachidonic acid metabolism pathway
Ether lipid metabolism pathway
Linoleic acid metabolism pathway
alpha-Linolenic acid metabolism pathway
Vascular smooth muscle contraction pathway
Pancreatic secretion pathway
Fat digestion and absorption pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME | |||||||||
| KEGG |
alpha-Linolenic acid metabolism pathway
Arachidonic acid metabolism pathway
Glycerophospholipid metabolism pathway
Linoleic acid metabolism pathway
Ether lipid metabolism pathway
Vascular smooth muscle contraction pathway
Fat digestion and absorption pathway
Pancreatic secretion pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | F6UTM6 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 69836 | ||||||||
| UniGene | Mm.30268 | ||||||||
| RefSeq | XM_006514062 NM_023530 XM_006514061 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS23864 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| MGI ID | MGI:1917086 | ||||||||
| MGI Symbol | Pla2g12b | ||||||||
| EMBL | AC022699 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 69836 | ||||||||