Mus musculus Gene: Mlf1ip
Summary
InnateDB Gene IDBG-154089.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Mlf1ip
Gene Name myeloid leukemia factor 1 interacting protein
Synonyms 1700029A22Rik; Mlf1ip
Species Mus musculus
Ensembl Gene ENSMUSG00000031629
Encoded Proteins
myeloid leukemia factor 1 interacting protein
myeloid leukemia factor 1 interacting protein
myeloid leukemia factor 1 interacting protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151725:
The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). MLF1IP, or CENPU, is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:46552055-46580007
Strand Forward strand
Band B1.1
Transcripts
ENSMUST00000034045 ENSMUSP00000034045
ENSMUST00000093518 ENSMUSP00000091239
ENSMUST00000135432 ENSMUSP00000120321
ENSMUST00000153908
ENSMUST00000129371
ENSMUST00000122838
ENSMUST00000136724
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 31 interaction(s) predicted by orthology.
Predicted by orthology
Total 31 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0043009 chordate embryonic development
Cellular Component
GO:0000777 condensed chromosome kinetochore
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005815 microtubule organizing center
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Cell Cycle, Mitotic pathway
Chromosome Maintenance pathway
Separation of Sister Chromatids pathway
Resolution of Sister Chromatid Cohesion pathway
Cell Cycle pathway
M Phase pathway
Mitotic Metaphase and Anaphase pathway
Mitotic Prometaphase pathway
Nucleosome assembly pathway
Deposition of new CENPA-containing nucleosomes at the centromere pathway
Mitotic Anaphase pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Deposition of new CENPA-containing nucleosomes at the centromere pathway
Resolution of Sister Chromatid Cohesion pathway
Mitotic Prometaphase pathway
Separation of Sister Chromatids pathway
Chromosome Maintenance pathway
Nucleosome assembly pathway
Cell Cycle pathway
M Phase pathway
Mitotic Anaphase pathway
Cell Cycle, Mitotic pathway
Mitotic Metaphase and Anaphase pathway
KEGG
INOH
PID NCI
PLK1 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.22108
RefSeq NM_027973 XM_006509498
OMIM
CCDS CCDS22292
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas