InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Naa10

Summary

InnateDB Gene

IDBG-154451.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Naa10

Gene Name

N(alpha)-acetyltransferase 10, NatA catalytic subunitNalpha acetyltransferase 10

Synonyms

2310039H09Rik; Ard1; Ard1a; Te2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031388

Encoded Proteins

IDBP-154453

N(alpha)-acetyltransferase 10, NatA catalytic subunitNalpha acetyltransferase 10

IDBP-169452

N(alpha)-acetyltransferase 10, NatA catalytic subunitNalpha acetyltransferase 10

IDBP-251864

N(alpha)-acetyltransferase 10, NatA catalytic subunitNalpha acetyltransferase 10

IDBP-251866

N(alpha)-acetyltransferase 10, NatA catalytic subunitNalpha acetyltransferase 10

IDBP-251868

N(alpha)-acetyltransferase 10, NatA catalytic subunitNalpha acetyltransferase 10

IDBP-251870

N(alpha)-acetyltransferase 10, NatA catalytic subunitNalpha acetyltransferase 10

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000102030:
N-alpha-acetylation is among the most common post-translational protein modifications in eukaryotic cells. This process involves the transfer of an acetyl group from acetyl-coenzyme A to the alpha-amino group on a nascent polypeptide and is essential for normal cell function. This gene encodes an N-terminal acetyltransferase that functions as the catalytic subunit of the major amino-terminal acetyltransferase A complex. Mutations in this gene are the cause of Ogden syndrome. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:73916873-73921944

Strand

Reverse strand

Band

A7.3

Transcripts

ENSMUST00000033763	ENSMUSP00000033763
ENSMUST00000096316	ENSMUSP00000094040
ENSMUST00000114391	ENSMUSP00000110033
ENSMUST00000114390	ENSMUSP00000110032
ENSMUST00000114389	ENSMUSP00000110031
ENSMUST00000114387	ENSMUSP00000110029
ENSMUST00000139105
ENSMUST00000141211
ENSMUST00000124446
ENSMUST00000143076
ENSMUST00000149591
ENSMUST00000153929

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.

Experimentally validated
Total	10 [view]
Protein-Protein	10 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	15 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004596	peptide alpha-N-acetyltransferase activity
GO:0005515	protein binding
GO:0008080	N-acetyltransferase activity
GO:0016407	acetyltransferase activity
GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups
GO:0043022	ribosome binding

Biological Process

GO:0006474	N-terminal protein amino acid acetylation
GO:0008152	metabolic process

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0031415	NatA complex

Orthologs

Species

Homo sapiens

Gene ID

Gene Order

ENSG00000102030

View Gene Order

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

KEGG

INOH

PID NCI

hif1apathway

Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Cross-References

SwissProt

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

NM_001177965 NM_019870 XM_006528158

OMIM

CCDS

CCDS30217 CCDS53102

HPRD

IMGT

MGI ID

MGI Symbol

EMBL

GenPept

RNA Seq Atlas