Mus musculus Gene: Cldn22
Summary
InnateDB Gene IDBG-154780.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cldn22
Gene Name claudin 22
Synonyms 2210404A22Rik; 5330431C14Rik; 9530051B05Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000038064
Encoded Proteins
claudin 22
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3' UTR of the Wwc2 gene (GeneID: 52357) on the opposite strand. [provided by RefSeq, Aug 2010]
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and overlaps the 3\' UTR of the Wwc2 gene (GeneID: 52357) on the opposite strand. [provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:47824482-47825475
Strand Forward strand
Band B1.1
Transcripts
ENSMUST00000038693 ENSMUSP00000041676
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005198 structural molecule activity
GO:0042802 identical protein binding
Biological Process
GO:0008150 biological_process
GO:0016338 calcium-independent cell-cell adhesion
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
GO:0005923 tight junction
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
Tight junction pathway
Cell adhesion molecules (CAMs) pathway
Leukocyte transendothelial migration pathway
Hepatitis C pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Tight junction interactions pathway
Cell-Cell communication pathway
Cell junction organization pathway
Cell-cell junction organization pathway
KEGG
Cell adhesion molecules (CAMs) pathway
Leukocyte transendothelial migration pathway
Tight junction pathway
Hepatitis C pathway
INOH
PID NCI
Cross-References
SwissProt Q9D7U6
TrEMBL
UniProt Splice Variant
Entrez Gene 75677
UniGene Mm.390033 Mm.468122
RefSeq NM_029383
OMIM
CCDS CCDS52550
HPRD
IMGT
MGI ID MGI:1922927
MGI Symbol Cldn22
EMBL AK008821
GenPept BAB25914
RNA Seq Atlas 75677