Mus musculus Protein: Cldn22
Summary
InnateDB Protein IDBP-154782.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cldn22
Protein Name claudin 22
Synonyms 2210404A22Rik; 5330431C14Rik; 9530051B05Rik;
Species Mus musculus
Ensembl Protein ENSMUSP00000041676
InnateDB Gene IDBG-154780 (Cldn22)
Protein Structure
UniProt Annotation
Function Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity. {ECO:0000250}.
Subcellular Localization Cell junction, tight junction {ECO:0000250}. Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005198 structural molecule activity
GO:0042802 identical protein binding
Biological Process
GO:0008150 biological_process
GO:0016338 calcium-independent cell-cell adhesion
Cellular Component
GO:0005575 cellular_component
GO:0005886 plasma membrane
GO:0005923 tight junction
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:1922927
InterPro IPR004031 PMP-22/EMP/MP20/Claudin superfamily
IPR006187 Claudin
PFAM PF00822
PF13903
PRINTS PR01077
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9D7U6
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 75677
UniGene Mm.468122
RefSeq NP_083659
MGI ID
MGI Symbol Cldn22
OMIM
CCDS CCDS52550
HPRD
IMGT
EMBL AK008821
GenPept BAB25914