Version 5.4
Mus musculus Gene: Akna
Summary
InnateDB Gene IDBG-154783.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Akna
Gene Name AT-hook transcription factor
Synonyms AI597013; mKIAA1968
Species Mus musculus
Ensembl Gene ENSMUSG00000039158
Encoded Proteins
IDBP-154785
AT-hook transcription factor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 21606955
Akna targeted deletion results in susceptibility to pathogen-induced systemic inflammation and causes sudden neonatal death.
InnateDB Annotation from Orthologs
Summary
PMID 21606955
[Homo sapiens] AKNA targeted deletion results in susceptibility to pathogen-induced systemic inflammation and causes sudden neonatal death. (Demonstrated in murine model)
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106948:
Gene Information
Type Protein coding
Genomic Location Chromosome 4:63367125-63403354
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000035724 ENSMUSP00000041614
ENSMUST00000140586
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003674 molecular_function
GO:0003677 DNA binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
GO:0045087 innate immune response (InnateDB)
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005575 cellular_component
GO:0005634 nucleus
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000106948
View Gene Order
ENSBTAG00000017306
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_001045514 XM_006537520 XM_006537521 XM_006537522 XM_006537523 XM_006537524 XM_006537525
OMIM
CCDS CCDS38777
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca