Mus musculus Gene: Plaur
Summary
InnateDB Gene IDBG-154827.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Plaur
Gene Name plasminogen activator, urokinase receptor
Synonyms Cd87; u-PAR; uPAR
Species Mus musculus
Ensembl Gene ENSMUSG00000046223
Encoded Proteins
plasminogen activator, urokinase receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
Plaur is required for optimal TLR2-induced neutrophil activation.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:24462500-24475873
Strand Forward strand
Band A3
Transcripts
ENSMUST00000002284 ENSMUSP00000002284
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0019899 enzyme binding
Biological Process
GO:0045087 innate immune response (InnateDB)
Cellular Component
GO:0005576 extracellular region
GO:0005887 integral component of plasma membrane
GO:0031225 anchored component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
Hemostasis pathway
Post-translational modification: synthesis of GPI-anchored proteins pathway
Metabolism of proteins pathway
Post-translational protein modification pathway
Dissolution of Fibrin Clot pathway
Attachment of GPI anchor to uPAR pathway
KEGG
Complement and coagulation cascades pathway
INOH
PID NCI
Cross-References
SwissProt P35456
TrEMBL Q545X5
UniProt Splice Variant
Entrez Gene 18793
UniGene
RefSeq NM_011113 XM_006539638 XM_006539639 XM_006539640 XM_006539641
OMIM
CCDS CCDS20950
HPRD
IMGT
MGI ID MGI:97612
MGI Symbol Plaur
EMBL AK002580 AK131951 AK144796 AK146827 CH466593 U12235 X62700 X62701
GenPept AAB60484 BAB22204 BAE20896 BAE26072 BAE27463 CAA44574 CAA44575 EDL24337
RNA Seq Atlas 18793