Version 5.4
Mus musculus Gene: Zfp346
Summary
InnateDB Gene IDBG-154868.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zfp346
Gene Name zinc finger protein 346
Synonyms Jaz; Znf346
Species Mus musculus
Ensembl Gene ENSMUSG00000021481
Encoded Proteins
IDBP-154870
zinc finger protein 346
IDBP-531762
zinc finger protein 346
IDBP-537998
zinc finger protein 346
IDBP-533979
zinc finger protein 346
IDBP-532725
zinc finger protein 346
IDBP-537268
zinc finger protein 346
IDBP-540489
zinc finger protein 346
IDBP-534154
zinc finger protein 346
IDBP-534527
zinc finger protein 346
IDBP-534636
zinc finger protein 346
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113761:
The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:55105311-55134825
Strand Forward strand
Band B1
Transcripts
ENSMUST00000021937 ENSMUSP00000021937
ENSMUST00000161018 ENSMUSP00000125154
ENSMUST00000161315 ENSMUSP00000124397
ENSMUST00000159278 ENSMUSP00000125078
ENSMUST00000159147 ENSMUSP00000124107
ENSMUST00000162476 ENSMUSP00000125743
ENSMUST00000161551 ENSMUSP00000124180
ENSMUST00000160660 ENSMUSP00000124034
ENSMUST00000162428 ENSMUSP00000125389
ENSMUST00000161077 ENSMUSP00000125204
ENSMUST00000162288
ENSMUST00000160310
ENSMUST00000162653
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003725 double-stranded RNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0019899 enzyme binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0043065 positive regulation of apoptotic process
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000113761
View Gene Order
ENSBTAG00000010541
Not yet available
Cross-References
SwissProt
TrEMBL E0CYH6
UniProt Splice Variant
Entrez Gene 26919
UniGene Mm.22795
RefSeq NM_012017 XM_006517260
OMIM
CCDS CCDS26539
HPRD
IMGT
MGI ID MGI:1349417
MGI Symbol Zfp346
EMBL AC123709 AC154610
GenPept
RNA Seq Atlas 26919

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca