Version 5.4
Mus musculus Gene: Trim2
Summary
InnateDB Gene IDBG-155139.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Trim2
Gene Name tripartite motif-containing 2
Synonyms mKIAA0517; narf
Species Mus musculus
Ensembl Gene ENSMUSG00000027993
Encoded Proteins
IDBP-155141
tripartite motif-containing 2
IDBP-155143
tripartite motif-containing 2
IDBP-266111
tripartite motif-containing 2
IDBP-266115
tripartite motif-containing 2
IDBP-266117
tripartite motif-containing 2
IDBP-266119
tripartite motif-containing 2
IDBP-536874
tripartite motif-containing 2
IDBP-541827
tripartite motif-containing 2
IDBP-541390
tripartite motif-containing 2
IDBP-536322
tripartite motif-containing 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000109654:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. Its function has not been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:84160439-84305446
Strand Reverse strand
Band F1
Transcripts
ENSMUST00000065380 ENSMUSP00000069922
ENSMUST00000054990 ENSMUSP00000049902
ENSMUST00000107695 ENSMUSP00000103323
ENSMUST00000107693 ENSMUSP00000103321
ENSMUST00000107692 ENSMUSP00000103320
ENSMUST00000107691 ENSMUSP00000103319
ENSMUST00000128574
ENSMUST00000140568
ENSMUST00000137596
ENSMUST00000156347
ENSMUST00000122849 ENSMUSP00000120981
ENSMUST00000132283 ENSMUSP00000118888
ENSMUST00000147901 ENSMUSP00000121055
ENSMUST00000136651
ENSMUST00000140856
ENSMUST00000154152 ENSMUSP00000115914
ENSMUST00000152953
ENSMUST00000136805
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Experimentally validated
Total 8 [view]
Protein-Protein 8 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0017022 myosin binding
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
GO:0043523 regulation of neuron apoptotic process
Cellular Component
GO:0005622 intracellular
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000109654
View Gene Order
ENSBTAG00000008816
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.397665 Mm.408158 Mm.408850 Mm.447490 Mm.44876 Mm.474162 Mm.487650 Mm.487876 Mm.489428
RefSeq NM_001271725 NM_001271726 NM_001271727 NM_001271728 NM_030706 XM_006502361 XM_006502362 XM_006502363 XM_006502364 XM_006502365 XM_006502366 XM_006502367 XM_006502368
OMIM
CCDS CCDS17437 CCDS71256 CCDS71257
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca