InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Plxna3

Summary

InnateDB Gene

IDBG-156039.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Plxna3

Gene Name

plexin A3

Synonyms

mKIAA4078; PlexA3; Plxa3; Plxn3; Plxn4; SEX

Species

Mus musculus

Ensembl Gene

ENSMUSG00000031398

Encoded Proteins

IDBP-156041

plexin A3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130827:
The protein encoded by this gene is a member of the plexin class of proteins. The encoded protein is a transmembrane protein that is exposed on the cell surface. This gene is thought to be involved in epithelial and neural tissue development. [provided by RefSeq, May 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:74329066-74344689

Strand

Forward strand

Band

A7.3

Transcripts

ENSMUST00000004326	ENSMUSP00000004326
ENSMUST00000136114
ENSMUST00000154062
ENSMUST00000142236
ENSMUST00000152376
ENSMUST00000139323
ENSMUST00000152317
ENSMUST00000148726
ENSMUST00000137484

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004872	receptor activity
GO:0005515	protein binding
GO:0017154	semaphorin receptor activity

Biological Process

GO:0007165	signal transduction
GO:0007275	multicellular organismal development
GO:0007411	axon guidance
GO:0021612	facial nerve structural organization
GO:0021637	trigeminal nerve structural organization
GO:0021766	hippocampus development
GO:0021785	branchiomotor neuron axon guidance
GO:0021860	pyramidal neuron development
GO:0048843	negative regulation of axon extension involved in axon guidance
GO:0050919	negative chemotaxis
GO:0051495	positive regulation of cytoskeleton organization
GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance