Version 5.4
Mus musculus Gene: Tysnd1
Summary
InnateDB Gene IDBG-156232.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Tysnd1
Gene Name trypsin domain containing 1
Synonyms 1300019N10Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000020087
Encoded Proteins
IDBP-156234
trypsin domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix. The full-length protein undergoes self-cleavage to produce shorter, potentially inactive, peptides. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:61695514-61702773
Strand Forward strand
Band B4
Transcripts
ENSMUST00000020284 ENSMUSP00000020284
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0002020 protease binding
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0042802 identical protein binding
Biological Process
GO:0006508 proteolysis
GO:0016485 protein processing
GO:0031998 regulation of fatty acid beta-oxidation
GO:0051260 protein homooligomerization
Cellular Component
GO:0005777 peroxisome
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000156521
View Gene Order
ENSBTAG00000038845
Not yet available
Cross-References
SwissProt Q9DBA6
TrEMBL
UniProt Splice Variant
Entrez Gene 71767
UniGene Mm.71514
RefSeq NM_027912 XM_006514168
OMIM
CCDS CCDS48575
HPRD
IMGT
MGI ID MGI:1919017
MGI Symbol Tysnd1
EMBL AK005069 AK154513 BC119320
GenPept AAI19321 BAB23793 BAE32642
RNA Seq Atlas 71767

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca