Version 5.4
Mus musculus Gene: Entpd5
Summary
InnateDB Gene IDBG-156587.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Entpd5
Gene Name ectonucleoside triphosphate diphosphohydrolase 5
Synonyms AI196558; AI987697; Cd39l4; ER-UDPase; mNTPase; NTPDase-5; NTPDase5; Pcph
Species Mus musculus
Ensembl Gene ENSMUSG00000021236
Encoded Proteins
IDBP-156589
ectonucleoside triphosphate diphosphohydrolase 5
IDBP-156591
ectonucleoside triphosphate diphosphohydrolase 5
IDBP-260622
ectonucleoside triphosphate diphosphohydrolase 5
IDBP-401330
ectonucleoside triphosphate diphosphohydrolase 5
IDBP-401329
ectonucleoside triphosphate diphosphohydrolase 5
IDBP-401328
ectonucleoside triphosphate diphosphohydrolase 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000187097:
The protein encoded by this gene is similar to E-type nucleotidases (NTPases)/ecto-ATPase/apyrases. NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD5 contains 4 apyrase-conserved regions which is characteristic of NTPases. [provided by RefSeq, Jan 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:84373857-84409029
Strand Reverse strand
Band D1
Transcripts
ENSMUST00000021662 ENSMUSP00000021662
ENSMUST00000072061 ENSMUSP00000071939
ENSMUST00000110272 ENSMUSP00000105901
ENSMUST00000120942 ENSMUSP00000112516
ENSMUST00000122194 ENSMUSP00000113106
ENSMUST00000117286 ENSMUSP00000114011
ENSMUST00000135061
ENSMUST00000136511
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004382 guanosine-diphosphatase activity
GO:0016787 hydrolase activity
GO:0045134 uridine-diphosphatase activity
Biological Process
GO:0006487 protein N-linked glycosylation
GO:0008152 metabolic process
GO:0008283 cell proliferation
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling
GO:0016049 cell growth
GO:0045821 positive regulation of glycolytic process
GO:0046034 ATP metabolic process
GO:0051084 'de novo' posttranslational protein folding
Cellular Component
GO:0005576 extracellular region
GO:0005783 endoplasmic reticulum
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000187097
View Gene Order
ENSBTAG00000020334
Not yet available
Pathways
NETPATH
REACTOME
KEGG
mmu00240
Pyrimidine metabolism pathway
mmu00230
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00230
Purine metabolism pathway
INOH
INOH website
Purine nucleotides nucleosides metabolism pathway
INOH website
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.10211 Mm.486864
RefSeq NM_001026214 NM_001286049 NM_001286058 NM_007647 XM_006515446 XM_006515447 XM_006515448 XM_006515449 XM_006515450 XM_006515451
OMIM
CCDS CCDS26045 CCDS36491
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca