Version 5.4
Mus musculus Gene: Ak3
Summary
InnateDB Gene IDBG-156789.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Ak3
Gene Name adenylate kinase 3
Synonyms AA407498; AI506714; AK-3; Ak3l; Ak3l1; Akl3l
Species Mus musculus
Ensembl Gene ENSMUSG00000024782
Encoded Proteins
IDBP-156791
adenylate kinase 3
IDBP-540905
adenylate kinase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147853:
The protein encoded by this gene is a GTP:ATP phosphotransferase that is found in the mitochondrial matrix. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:29020833-29047961
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000025696 ENSMUSP00000025696
ENSMUST00000125587 ENSMUSP00000121867
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004017 adenylate kinase activity
GO:0005524 ATP binding
GO:0005525 GTP binding
GO:0016776 phosphotransferase activity, phosphate group as acceptor
GO:0046899 nucleoside triphosphate adenylate kinase activity
Biological Process
GO:0046033 AMP metabolic process
GO:0046039 GTP metabolic process
GO:0046041 ITP metabolic process
GO:0046051 UTP metabolic process
GO:0046939 nucleotide phosphorylation
Cellular Component
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000147853
View Gene Order
ENSBTAG00000017147
Not yet available
Pathways
NETPATH
REACTOME
REACT_224553
Hemostasis pathway
REACT_198649
Factors involved in megakaryocyte development and platelet production pathway
KEGG
mmu00230
Purine metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_24970
Factors involved in megakaryocyte development and platelet production pathway
REACT_604
Hemostasis pathway
REACT_215067
Factors involved in megakaryocyte development and platelet production pathway
REACT_212196
Hemostasis pathway
KEGG
hsa00230
Purine metabolism pathway
INOH
INOH website
Pyrimidine nucleotides nucleosides metabolism pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 56248
UniGene Mm.196067 Mm.441343
RefSeq NM_021299
OMIM
CCDS CCDS29730
HPRD
IMGT
MGI ID MGI:1860835
MGI Symbol Ak3
EMBL
GenPept
RNA Seq Atlas 56248

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca