Version 5.4
Mus musculus Gene: Rnf181
Summary
InnateDB Gene IDBG-157153.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rnf181
Gene Name ring finger protein 181
Synonyms 1700047F16Rik; 2500002L14Rik; 6230415N01Rik; C77350
Species Mus musculus
Ensembl Gene ENSMUSG00000055850
Encoded Proteins
IDBP-157155
ring finger protein 181
IDBP-157157
ring finger protein 181
IDBP-252495
ring finger protein 181
IDBP-788668
ring finger protein 181
IDBP-536727
ring finger protein 181
IDBP-788671
ring finger protein 181
IDBP-788672
ring finger protein 181
IDBP-788674
ring finger protein 181
IDBP-788676
ring finger protein 181
IDBP-788678
ring finger protein 181
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168894:
RNF181 binds the integrin alpha-IIb (ITGA2B; MIM 607759)/beta-3 (ITGB3; MIM 173470) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008 [PubMed 18331836]).[supplied by OMIM, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:72359714-72362721
Strand Reverse strand
Band C1
Transcripts
ENSMUST00000069595 ENSMUSP00000070370
ENSMUST00000069580 ENSMUSP00000066128
ENSMUST00000114095 ENSMUSP00000109729
ENSMUST00000125554 ENSMUSP00000138229
ENSMUST00000130064 ENSMUSP00000115187
ENSMUST00000154098 ENSMUSP00000138327
ENSMUST00000149296 ENSMUSP00000138442
ENSMUST00000129233 ENSMUSP00000138365
ENSMUST00000126065 ENSMUSP00000138309
ENSMUST00000151063 ENSMUSP00000138670
ENSMUST00000136707
ENSMUST00000133978
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
GO:0051865 protein autoubiquitination
Cellular Component
GO:0005575 cellular_component
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000168894
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.304411 Mm.486722 Mm.489598
RefSeq NM_025607
OMIM
CCDS CCDS20240
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca