Version 5.4
Mus musculus Protein: Rnf181
Summary
InnateDB Protein IDBP-157157.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Rnf181
Protein Name ring finger protein 181
Synonyms 1700047F16Rik; 2500002L14Rik; 6230415N01Rik; C77350;
Species Mus musculus
Ensembl Protein ENSMUSP00000066128
InnateDB Gene IDBG-157153 (Rnf181)
Protein Structure
UniProt Annotation
Function E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. {ECO:0000250}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.
Predicted by orthology
Total 17 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
GO:0046872 metal ion binding
Biological Process
GO:0016567 protein ubiquitination
GO:0051865 protein autoubiquitination
Cellular Component
GO:0005575 cellular_component
Protein Structure and Domains
PDB ID MGI:1913760
InterPro IPR001841 Zinc finger, RING-type
IPR018957 Zinc finger, C3HC4 RING-type
PFAM PF13639
PF14634
PF00097
PRINTS
PIRSF
SMART SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CY62
PhosphoSite PhosphoSite-Q9CY62
TrEMBL
UniProt Splice Variant
Entrez Gene 66510
UniGene Mm.489598
RefSeq NP_079883
MGI ID
MGI Symbol Rnf181
OMIM
CCDS CCDS20240
HPRD
IMGT
EMBL AK010854 AK014094 AK018849 AK159788 AK166904 AK166995 AK167396 AK167633 AK167935 AK168670 BC005559 BC083119
GenPept AAH05559 AAH83119 BAB27224 BAB31462 BAC25424 BAE35371 BAE39106 BAE39174 BAE39485 BAE39684 BAE39939 BAE40520

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca