InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ndufb3

Summary

InnateDB Gene

IDBG-157207.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndufb3

Gene Name

NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3

Synonyms

2700033I16Rik; AI415450

Species

Mus musculus

Ensembl Gene

ENSMUSG00000026032

Encoded Proteins

IDBP-157209

NADH dehydrogenase (ubiquinone) 1 beta subcomplex 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119013:
This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein. Humans have multiple pseudogenes of this gene. [provided by RefSeq, Mar 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:58586384-58595964

Strand

Forward strand

Band

C1.3

Transcripts

ENSMUST00000027193

ENSMUSP00000027193

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0008150	biological_process
GO:0022900	electron transport chain

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005747	mitochondrial respiratory chain complex I
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome