InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: NDUFB3

Summary

InnateDB Gene

IDBG-643200.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NDUFB3

Gene Name

NADH dehydrogenase

Synonyms

CI-B12

Species

Bos taurus

Ensembl Gene

ENSBTAG00000012760

Encoded Proteins

IDBP-695739

NADH dehydrogenase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119013:
This gene encodes an accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which is the first enzyme in the electron transport chain of mitochondria. This protein localizes to the inner membrane of the mitochondrion as a single-pass membrane protein. Mutations in this gene contribute to mitochondrial complex 1 deficiency. Alternative splicing results in multiple transcript variants encoding the same protein. Humans have multiple pseudogenes of this gene. [provided by RefSeq, Mar 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:90077970-90088465

Strand

Forward strand

Band

Transcripts

ENSBTAT00000016957

ENSBTAP00000016957

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession

GO Term

Biological Process

GO:0022900	electron transport chain
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005747	mitochondrial respiratory chain complex I
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0070062	extracellular vesicular exosome
GO:0070469	respiratory chain