Version 5.4
Mus musculus Gene: Kif27
Summary
InnateDB Gene IDBG-158134.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Kif27
Gene Name kinesin family member 27
Synonyms 4930517I18Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000060176
Encoded Proteins
IDBP-158136
kinesin family member 27
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000165115:
This gene is a member of the KIF27 (kinesin 4) sub-family of the mammalian kinesin family. The gene is an ortholog of the Drosophila Cos2 gene, which plays an important role in the Hedgehog signaling pathway. The encoded protein contains an N-terminal motor domain which includes nucleotide-binding and microtubule-interacting regions, a stalk domain containing a predicted coiled coil motif and a C-terminal tail domain. Alternatively spliced transcript variants have been observed for this gene. Pseudogenes associated with this gene are located on chromosome 9. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 13:58287516-58354862
Strand Reverse strand
Band B1
Transcripts
ENSMUST00000043605 ENSMUSP00000043304
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008017 microtubule binding
Biological Process
GO:0003351 epithelial cilium movement
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
GO:0021591 ventricular system development
GO:0042384 cilium assembly
Cellular Component
GO:0005737 cytoplasm
GO:0005871 kinesin complex
GO:0005874 microtubule
GO:0005929 cilium
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000165115
View Gene Order
ENSBTAG00000020436
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_10
Hedgehog pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt Q7M6Z4
TrEMBL
UniProt Splice Variant
Entrez Gene 75050
UniGene Mm.446094
RefSeq NM_175214 XM_006517426 XM_006517427 XM_006517428 XM_006517429 XM_006517430 XM_006517431 XM_006517432 XM_006517433 XM_006517434 XM_006517435 XM_006517436
OMIM
CCDS CCDS26570
HPRD
IMGT
MGI ID MGI:1922300
MGI Symbol Kif27
EMBL AK032912 BC116646 BK001056
GenPept AAI16647 BAC28083 DAA01314
RNA Seq Atlas 75050

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca