Version 5.4
Mus musculus Gene: Qrfp
Summary
InnateDB Gene IDBG-158382.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Qrfp
Gene Name pyroglutamylated RFamide peptide
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000043102
Encoded Proteins
IDBP-158384
pyroglutamylated RFamide peptide
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188710:
The P518 precursor protein can be processed into several RF (arg-phe)-amide peptides, including P518. RF-amide peptides share a common C-terminal motif and are involved in cell signaling through G protein-coupled receptors (Jiang et al., 2003 [PubMed 12714592]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:31806166-31810580
Strand Reverse strand
Band B
Transcripts
ENSMUST00000057407 ENSMUSP00000055746
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005184 neuropeptide hormone activity
GO:0031854 orexigenic neuropeptide QRFP receptor binding
Biological Process
GO:0007218 neuropeptide signaling pathway
GO:0007625 grooming behavior
GO:0007626 locomotory behavior
GO:0045777 positive regulation of blood pressure
GO:0060259 regulation of feeding behavior
Cellular Component
GO:0005575 cellular_component
GO:0005576 extracellular region
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000188710
View Gene Order
Pathways
NETPATH
REACTOME
REACT_223625
GPCR downstream signaling pathway
REACT_254215
Signaling by GPCR pathway
REACT_261161
Class A/1 (Rhodopsin-like receptors) pathway
REACT_188573
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_231434
Orexin and neuropeptides FF and QRFP bind to their respective receptors pathway
REACT_231468
GPCR ligand binding pathway
REACT_235286
Peptide ligand-binding receptors pathway
REACT_207651
G alpha (q) signalling events pathway
REACT_188257
Signal Transduction pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_16973
Orexin and neuropeptides FF and QRFP bind to their respective receptors pathway
REACT_14819
Peptide ligand-binding receptors pathway
REACT_14828
Class A/1 (Rhodopsin-like receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8CE23
TrEMBL
UniProt Splice Variant
Entrez Gene 227717
UniGene Mm.185027
RefSeq NM_183424
OMIM
CCDS CCDS15902
HPRD
IMGT
MGI ID MGI:3630329
MGI Symbol Qrfp
EMBL AB109628 AK029144 AL929275
GenPept BAC26323 BAC98937 CAM26566
RNA Seq Atlas 227717

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca