InnateDB Protein
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IDBP-158384.6
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Qrfp
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Protein Name
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pyroglutamylated RFamide peptide
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Synonyms
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000055746
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InnateDB Gene
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IDBG-158382 (Qrfp)
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Protein Structure
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Function |
Stimulates feeding and grooming behavior, metabolic rate and locomotor activity and increases blood pressure. May have orexigenic activity. May promote aldosterone secretion by the adrenal gland. {ECO:0000269PubMed:16648250}.
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Subcellular Localization |
Secreted.
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Disease Associations |
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Tissue Specificity |
Expressed in the brain with highest levels in the periventricular hypothalamic nucleus and lateral hypothalamic areas. Expressed at moderate levels in the adrenal gland, eye, heart, intestine, liver, lung, kidney, mesenteric lymph node, ovary, placenta, Peyer patches, skin, spleen, stomach, testis, thymus and uterus. {ECO:0000269PubMed:12714592, ECO:0000269PubMed:16648250}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
Accession |
GO Term |
GO:0005184
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neuropeptide hormone activity
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GO:0031854
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orexigenic neuropeptide QRFP receptor binding
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:3630329
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InterPro |
IPR024565
Orexigenic neuropeptide QRFP/P518
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PFAM |
PF11109
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8CE23
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
227717
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UniGene |
Mm.185027
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RefSeq |
NP_906269
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MGI ID |
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MGI Symbol |
Qrfp
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OMIM |
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CCDS |
CCDS15902
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HPRD |
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IMGT |
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EMBL |
AB109628
AK029144
AL929275
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GenPept |
BAC26323
BAC98937
CAM26566
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