Version 5.4
Mus musculus Gene: Bloc1s4
Summary
InnateDB Gene IDBG-158434.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Bloc1s4
Gene Name biogenesis of organelles complex-1, subunit 4, cappuccino
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000060708
Encoded Proteins
IDBP-158436
cappuccino
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186222:
This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. A similar protein in mouse is a component of a protein complex termed biogenesis of lysosome-related organelles complex 1 (BLOC-1), and is a model for Hermansky-Pudlak syndrome. The encoded protein may play a role in intracellular vesicular trafficking. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:36747374-36748679
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000071949 ENSMUSP00000071840
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0008089 anterograde axon cargo transport
GO:0031175 neuron projection development
GO:0032438 melanosome organization
GO:0048490 anterograde synaptic vesicle transport
GO:0050885 neuromuscular process controlling balance
GO:0070527 platelet aggregation
Cellular Component
GO:0005737 cytoplasm
GO:0031083 BLOC-1 complex
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000186222
View Gene Order
ENSBTAG00000003766
Not yet available
Pathways
NETPATH
REACTOME
REACT_209837
Membrane Trafficking pathway
REACT_232671
Golgi Associated Vesicle Biogenesis pathway
REACT_243409
trans-Golgi Network Vesicle Budding pathway
REACT_234979
Clathrin derived vesicle budding pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19400
Golgi Associated Vesicle Biogenesis pathway
REACT_19187
Clathrin derived vesicle budding pathway
REACT_11235
trans-Golgi Network Vesicle Budding pathway
REACT_11123
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q8VED2
TrEMBL
UniProt Splice Variant
Entrez Gene 117197
UniGene Mm.46744
RefSeq NM_133724
OMIM
CCDS CCDS19241
HPRD
IMGT
MGI ID MGI:1929230
MGI Symbol Bloc1s4
EMBL AY186603 BC019169
GenPept AAH19169 AAO65401
RNA Seq Atlas 117197

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca