Version 5.4
Mus musculus Gene: Reg3g
Summary
InnateDB Gene IDBG-158682.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Reg3g
Gene Name regenerating islet-derived 3 gamma
Synonyms AI449515
Species Mus musculus
Ensembl Gene ENSMUSG00000030017
Encoded Proteins
IDBP-158684
regenerating islet-derived 3 gamma
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation
Summary
PMID 24345802
Reg3g has a protective role against mucosal infection by binding to Gram-negative and Gram-positive bacteria, and influences mucus distribution in the ileum and contributes to mucosal protection.
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:78466269-78468872
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000032089 ENSMUSP00000032089
ENSMUST00000176650
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0030246 carbohydrate binding
Biological Process
GO:0002755 MyD88-dependent toll-like receptor signaling pathway
GO:0006953 acute-phase response
GO:0010838 positive regulation of keratinocyte proliferation
GO:0045087 innate immune response (InnateDB)
GO:0045617 negative regulation of keratinocyte differentiation
GO:0050830 defense response to Gram-positive bacterium
GO:0090303 positive regulation of wound healing
Cellular Component
GO:0005576 extracellular region
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt O09049
TrEMBL Q545I1
UniProt Splice Variant
Entrez Gene 19695
UniGene Mm.252385
RefSeq NM_011260
OMIM
CCDS CCDS20258
HPRD
IMGT
MGI ID MGI:109406
MGI Symbol Reg3g
EMBL AK008446 AK008608 BC061139 CH466523 D63361 D63362
GenPept AAH61139 BAA18930 BAA18931 BAB25674 BAB25774 EDK99020
RNA Seq Atlas 19695

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca