InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Gyk

Summary

InnateDB Gene

IDBG-158822.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gyk

Gene Name

glycerol kinase

Synonyms

D930012N15Rik; GK

Species

Mus musculus

Ensembl Gene

ENSMUSG00000025059

Encoded Proteins

IDBP-158824

glycerol kinase

IDBP-252728

glycerol kinase

IDBP-539430

glycerol kinase

IDBP-540809

glycerol kinase

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198814:
The protein encoded by this gene belongs to the FGGY kinase family. This protein is a key enzyme in the regulation of glycerol uptake and metabolism. It catalyzes the phosphorylation of glycerol by ATP, yielding ADP and glycerol-3-phosphate. Mutations in this gene are associated with glycerol kinase deficiency (GKD). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome X:85701937-85776819

Strand

Reverse strand

Band

Transcripts

ENSMUST00000026039	ENSMUSP00000026039
ENSMUST00000113978	ENSMUSP00000109611
ENSMUST00000156390	ENSMUSP00000119564
ENSMUST00000142152	ENSMUSP00000120754
ENSMUST00000152221
ENSMUST00000122950
ENSMUST00000124386
ENSMUST00000125081

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	11 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004370	glycerol kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016773	phosphotransferase activity, alcohol group as acceptor

Biological Process

GO:0005975	carbohydrate metabolic process
GO:0006071	glycerol metabolic process
GO:0006072	glycerol-3-phosphate metabolic process
GO:0006641	triglyceride metabolic process
GO:0016310	phosphorylation
GO:0019563	glycerol catabolic process
GO:0042593	glucose homeostasis
GO:0046167	glycerol-3-phosphate biosynthetic process