Mus musculus Protein: Gyk
Summary
InnateDB Protein IDBP-252728.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gyk
Protein Name glycerol kinase
Synonyms D930012N15Rik; GK;
Species Mus musculus
Ensembl Protein ENSMUSP00000109611
InnateDB Gene IDBG-158822 (Gyk)
Protein Structure
UniProt Annotation
Function Key enzyme in the regulation of glycerol uptake and metabolism. {ECO:0000250}.
Subcellular Localization Mitochondrion outer membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm {ECO:0000250}. Note=Bound to the mitochondrial surface or cytoplasmic. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004370 glycerol kinase activity
GO:0005524 ATP binding
GO:0016773 phosphotransferase activity, alcohol group as acceptor
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0006071 glycerol metabolic process
GO:0006072 glycerol-3-phosphate metabolic process
GO:0006641 triglyceride metabolic process
GO:0016310 phosphorylation
GO:0019563 glycerol catabolic process
GO:0042593 glucose homeostasis
GO:0046167 glycerol-3-phosphate biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005741 mitochondrial outer membrane
GO:0005829 cytosol
Protein Structure and Domains
PDB ID MGI:106594
InterPro IPR005999 Glycerol kinase
IPR018484 Carbohydrate kinase, FGGY, N-terminal
IPR018485 Carbohydrate kinase, FGGY, C-terminal
PFAM PF00370
PF02782
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q64516
PhosphoSite PhosphoSite-Q64516
TrEMBL Q9CVH5
UniProt Splice Variant
Entrez Gene 14933
UniGene Mm.462245
RefSeq XP_006527895
MGI ID
MGI Symbol Gyk
OMIM
CCDS
HPRD
IMGT
EMBL AK008186 AK044308 AK088373 AL645567 AL672056 BC003767 U48403
GenPept AAC52824 AAH03767 BAB25518 BAC31861 BAC40312 CAM16667 CAM16668 CAM25261 CAM25262