InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Tst

Summary

InnateDB Gene

IDBG-159102.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Tst

Gene Name

thiosulfate sulfurtransferase, mitochondrial

Synonyms

Rhodanese

Species

Mus musculus

Ensembl Gene

ENSMUSG00000044986

Encoded Proteins

IDBP-159106

thiosulfate sulfurtransferase, mitochondrial

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000128311:
This is one of two neighboring genes encoding similar proteins that each contain two rhodanese domains. The encoded protein is localized to the mitochondria and catalyzes the conversion of thiosulfate and cyanide to thiocyanate and sulfite. In addition, the protein interacts with 5S ribosomal RNA and facilitates its import into the mitochondria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 15:78399556-78405859

Strand

Reverse strand

Band

Transcripts

ENSMUST00000058659

ENSMUSP00000055743

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004792	thiosulfate sulfurtransferase activity
GO:0008097	5S rRNA binding

Biological Process

GO:0008152	metabolic process
GO:0030855	epithelial cell differentiation
GO:0035928	rRNA import into mitochondrion
GO:0051029	rRNA transport

Cellular Component

GO:0005615	extracellular space
GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005759	mitochondrial matrix
GO:0005886	plasma membrane
GO:0070062	extracellular vesicular exosome