Mus musculus Gene: Upk1b
Summary
InnateDB Gene IDBG-160731.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Upk1b
Gene Name uroplakin 1B
Synonyms AI413235; Tspan20; UPIb; Upk1
Species Mus musculus
Ensembl Gene ENSMUSG00000049436
Encoded Proteins
uroplakin 1B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114638:
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is found in the asymmetrical unit membrane (AUM) where it can form a complex with other transmembrane 4 superfamily proteins. It may play a role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:38773184-38800203
Strand Reverse strand
Band B4
Transcripts
ENSMUST00000057767 ENSMUSP00000052469
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0030855 epithelial cell differentiation
Cellular Component
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt Q9Z2C6
TrEMBL
UniProt Splice Variant
Entrez Gene 22268
UniGene Mm.130793 Mm.490676
RefSeq NM_178924
OMIM
CCDS CCDS28174
HPRD
IMGT
MGI ID MGI:98912
MGI Symbol Upk1b
EMBL AF073956 AF274865 AK053004 AK083101 AK086926 BC046604
GenPept AAD02834 AAH46604 AAM97593 BAC35237 BAC38760 BAC39763
RNA Seq Atlas 22268