Version 5.4
Mus musculus Gene: Vsig4
Summary
InnateDB Gene IDBG-160903.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Vsig4
Gene Name V-set and immunoglobulin domain containing 4
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000044206
Encoded Proteins
IDBP-160905
V-set and immunoglobulin domain containing 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155659:
This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:96247203-96293438
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000050707 ENSMUSP00000051521
ENSMUST00000146830
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0032703 negative regulation of interleukin-2 production
GO:0042130 negative regulation of T cell proliferation
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000155659
View Gene Order
ENSBTAG00000015769
Not yet available
Cross-References
SwissProt
TrEMBL Q80WA3
UniProt Splice Variant
Entrez Gene 278180
UniGene Mm.26781
RefSeq NM_177789
OMIM
CCDS CCDS30288
HPRD
IMGT
MGI ID MGI:2679720
MGI Symbol Vsig4
EMBL AL831708 BC025105
GenPept AAH25105
RNA Seq Atlas 278180

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca