Version 5.4
Mus musculus Gene: Sik3
Summary
InnateDB Gene IDBG-161015.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sik3
Gene Name SIK family kinase 3
Synonyms 5730525O22Rik; 9030204A07Rik; AI447252; AI846254; AI849445; mKIAA0999; Qsk; SIK-3
Species Mus musculus
Ensembl Gene ENSMUSG00000034135
Encoded Proteins
IDBP-401171
SIK family kinase 3
IDBP-401170
SIK family kinase 3
IDBP-532008
SIK family kinase 3
IDBP-538835
SIK family kinase 3
IDBP-537610
SIK family kinase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160584:
Gene Information
Type Protein coding
Genomic Location Chromosome 9:46012820-46224194
Strand Forward strand
Band A5.2
Transcripts
ENSMUST00000120463 ENSMUSP00000112749
ENSMUST00000120247 ENSMUSP00000112859
ENSMUST00000126865 ENSMUSP00000121032
ENSMUST00000122865 ENSMUSP00000115981
ENSMUST00000153152
ENSMUST00000138338 ENSMUSP00000115805
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0001958 endochondral ossification
GO:0006468 protein phosphorylation
GO:0032880 regulation of protein localization
GO:0035108 limb morphogenesis
GO:0035264 multicellular organism growth
GO:0048705 skeletal system morphogenesis
GO:0060351 cartilage development involved in endochondral bone morphogenesis
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Gene ID
Gene Order
ENSG00000160584
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
lkb1_pathway
LKB1 signaling events
Cross-References
SwissProt
TrEMBL E9PU87
UniProt Splice Variant
Entrez Gene 70661
UniGene Mm.219459 Mm.404498 Mm.418402
RefSeq NM_027498
OMIM
CCDS CCDS23140
HPRD
IMGT
MGI ID MGI:2446296
MGI Symbol Sik3
EMBL AC116503 AC122273
GenPept
RNA Seq Atlas 70661

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca