Version 5.4
Homo sapiens Gene: SIK3
Summary
InnateDB Gene IDBG-72825.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIK3
Gene Name SIK family kinase 3
Synonyms QSK; SIK-3
Species Homo sapiens
Ensembl Gene ENSG00000160584
Encoded Proteins
IDBP-72827
SIK family kinase 3
IDBP-383404
SIK family kinase 3
IDBP-383412
SIK family kinase 3
IDBP-383413
SIK family kinase 3
IDBP-383415
SIK family kinase 3
IDBP-383419
SIK family kinase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:116843402-117098437
Strand Reverse strand
Band q23.3
Transcripts
ENST00000375300 ENSP00000364449
ENST00000445177 ENSP00000391295
ENST00000454905 ENSP00000392849
ENST00000446921 ENSP00000390442
ENST00000415541 ENSP00000392761
ENST00000413553 ENSP00000414347
ENST00000488337
ENST00000465421
ENST00000480468
ENST00000480222
ENST00000472648
ENST00000497049
ENST00000485363
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000287 magnesium ion binding
GO:0004672 protein kinase activity
GO:0004674 protein serine/threonine kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016772 transferase activity, transferring phosphorus-containing groups
Biological Process
GO:0001958 endochondral ossification
GO:0006468 protein phosphorylation
GO:0032880 regulation of protein localization
GO:0035108 limb morphogenesis
GO:0035264 multicellular organism growth
GO:0048705 skeletal system morphogenesis
GO:0060351 cartilage development involved in endochondral bone morphogenesis
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000034135
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
lkb1_pathway
LKB1 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.623495 Hs.625093 Hs.684067
RefSeq NM_001281748 NM_001281749 NM_025164 XM_005271481 XM_005271485 XM_005271486
HUGO
OMIM
CCDS CCDS60974 CCDS8379
HPRD 11121
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca