Version 5.4
Mus musculus Gene: Prx
Summary
InnateDB Gene IDBG-161168.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Prx
Gene Name periaxin
Synonyms L-Periaxin
Species Mus musculus
Ensembl Gene ENSMUSG00000053198
Encoded Proteins
IDBP-161170
periaxin
IDBP-161172
periaxin
IDBP-264714
periaxin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105227:
This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:27499324-27520214
Strand Forward strand
Band A3
Transcripts
ENSMUST00000098644 ENSMUSP00000096241
ENSMUST00000065487 ENSMUSP00000066110
ENSMUST00000108355 ENSMUSP00000103992
ENSMUST00000125990
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 9 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0043484 regulation of RNA splicing
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000105227
View Gene Order
ENSBTAG00000017333
Not yet available
Cross-References
SwissProt
TrEMBL E9QQ57
UniProt Splice Variant
Entrez Gene 19153
UniGene Mm.10119
RefSeq NM_198048 XM_006539665 NM_019412
OMIM
CCDS CCDS21023 CCDS39849
HPRD
IMGT
MGI ID MGI:108176
MGI Symbol Prx
EMBL AC158304
GenPept
RNA Seq Atlas 19153

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca