Version 5.4
Mus musculus Gene: Klf7
Summary
InnateDB Gene IDBG-161285.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klf7
Gene Name Kruppel-like factor 7 (ubiquitous)
Synonyms 9830124P08Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000025959
Encoded Proteins
IDBP-161287
Kruppel-like factor 7 (ubiquitous)
IDBP-252503
Kruppel-like factor 7 (ubiquitous)
IDBP-538904
Kruppel-like factor 7 (ubiquitous)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000118263:
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:64029447-64122282
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000055001 ENSMUSP00000054674
ENSMUST00000114086 ENSMUSP00000109720
ENSMUST00000135075 ENSMUSP00000120537
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0007409 axonogenesis
GO:0007411 axon guidance
GO:0045893 positive regulation of transcription, DNA-templated
GO:0048813 dendrite morphogenesis
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000118263
View Gene Order
ENSBTAG00000044097
Not yet available
Cross-References
SwissProt
TrEMBL A2AAB6
UniProt Splice Variant
Entrez Gene 93691
UniGene Mm.394909 Mm.458200 Mm.487374
RefSeq NM_033563 XM_006496350 XM_006496351 XM_006496354
OMIM
CCDS CCDS15003
HPRD
IMGT
MGI ID MGI:1935151
MGI Symbol Klf7
EMBL AL645646 AL645726
GenPept
RNA Seq Atlas 93691

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca