Mus musculus Gene: Pcdh15
Summary
InnateDB Gene IDBG-162009.5
Last Modified 2012-02-14 [Report errors or provide feedback]
Gene Symbol Pcdh15
Gene Name protocadherin 15
Synonyms av; BB078305; ENSMUSG00000046980; Gm9815; nmf19; Ush1f;
Species Mus musculus
Ensembl Gene ENSMUSG00000052613
Encoded Proteins
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
protocadherin 15
Protein Structure
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000150275:
This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:73099342-74646314
Strand Forward strand
Band B5.3
Transcripts
ENSMUST00000092420 ENSMUSP00000090076
ENSMUST00000064562 ENSMUSP00000068561
ENSMUST00000105429 ENSMUSP00000101069
ENSMUST00000105426 ENSMUSP00000101066
ENSMUST00000105424 ENSMUSP00000101064
ENSMUST00000123398
ENSMUST00000148572
ENSMUST00000156999
ENSMUST00000146682 ENSMUSP00000134863
ENSMUST00000136096 ENSMUSP00000121534
ENSMUST00000124046 ENSMUSP00000121130
ENSMUST00000131724 ENSMUSP00000122466
ENSMUST00000152655 ENSMUSP00000118201
ENSMUST00000149977 ENSMUSP00000118833
ENSMUST00000151116 ENSMUSP00000119662
ENSMUST00000147189 ENSMUSP00000122940
ENSMUST00000126920 ENSMUSP00000121939
ENSMUST00000131321 ENSMUSP00000122911
ENSMUST00000129404 ENSMUSP00000117731
ENSMUST00000155701 ENSMUSP00000135495
ENSMUST00000152819 ENSMUSP00000123647
ENSMUST00000125517 ENSMUSP00000115399
ENSMUST00000125055 ENSMUSP00000114326
ENSMUST00000125006 ENSMUSP00000120056
ENSMUST00000134009 ENSMUSP00000120618
ENSMUST00000147455
ENSMUST00000139106
ENSMUST00000128843
ENSMUST00000144302 ENSMUSP00000122606
ENSMUST00000127928
ENSMUST00000177420 ENSMUSP00000135849
ENSMUST00000177107 ENSMUSP00000135501
ENSMUST00000177128 ENSMUSP00000135888
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0001964 startle response
GO:0002009 morphogenesis of an epithelium
GO:0007015 actin filament organization
GO:0007156 homophilic cell adhesion
GO:0007601 visual perception
GO:0007605 sensory perception of sound
GO:0007626 locomotory behavior
GO:0007628 adult walking behavior
GO:0035058 nonmotile primary cilium assembly
GO:0035264 multicellular organism growth
GO:0042491 auditory receptor cell differentiation
GO:0048839 inner ear development
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
GO:0050973 detection of mechanical stimulus involved in equilibrioception
GO:0060013 righting reflex
GO:0060088 auditory receptor cell stereocilium organization
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral to membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Method
Confidence
Comments
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Not yet available
Non-SSD Ortholog
Possible paralog/unusual divergence/ gene prediction error
Cross-References
SwissProt
TrEMBL D3YTL2 D6RCH0 E9Q159 E9Q7D7 E9Q7R2 F6KJX4 F6KKG6 F6R5Z7 F6RBV2 F6WUN7 F6Y0A5 F6YP25 F7ASH0 F7D5J8 F7DFU0 F8VQ61 H3BKS0 Q0ZM15 Q0ZM16 Q0ZM18 Q0ZM21 Q0ZM22 Q0ZM23 Q0ZM24 Q0ZM25 Q3UTS7
UniProt Splice Variant
Entrez Gene 11994
UniGene Mm.338933 Mm.408656 Mm.479473
RefSeq NM_001142735 NM_001142736 NM_001142737 NM_001142738 NM_001142739 NM_001142740 NM_001142741 NM_001142742 NM_001142743 NM_001142746 NM_001142747 NM_001142748 NM_001142760 NM_023115
OMIM
CCDS CCDS35934 CCDS48594 CCDS48595 CCDS56711 CCDS56712 CCDS56713 CCDS56714 CCDS56715 CCDS56716 CCDS56717 CCDS56718 CCDS56719 CCDS56720 CCDS56721
HPRD
IMGT
MGI ID 1891428 MGI:1891428
MGI Symbol Pcdh15
EMBL AC108392 AC119894 AC121142 AC121602 AC121832 AC123032 AC123809 AC144802 AC147721 AC153858 AC158800 AC159477 AC186813 AC188091 AK139154 CAAA01110489 DQ354408 DQ354409 DQ354410 DQ354411 DQ354412 DQ354415 DQ354416 DQ354417 DQ354418 HQ404375 HQ420254
GenPept ABC79271 ABC79272 ABC79273 ABC79274 ABC79275 ABC79278 ABC79279 ABC79280 ABC79281 ADP09331 ADT91308 BAE23903
ImmGen Pcdh15 (murine)
RNA Seq Atlas 11994