Mus musculus Gene: Pcdh15

Summary
InnateDB Gene IDBG-162009.5
Last Modified 2012-02-14   [Report errors or provide feedback]
Gene Symbol Pcdh15
Gene Name protocadherin 15
Synonyms av; BB078305; ENSMUSG00000046980; Gm9815; nmf19; Ush1f
Species Mus musculus
Ensembl Gene ENSMUSG00000052613
Encoded Proteins
IDBP-162011 protocadherin 15
IDBP-162013 protocadherin 15
IDBP-270898 protocadherin 15
IDBP-270904 protocadherin 15
IDBP-270908 protocadherin 15
IDBP-712406
IDBP-538849 protocadherin 15
IDBP-532408 protocadherin 15
IDBP-536203 protocadherin 15
IDBP-537988 protocadherin 15
IDBP-538522 protocadherin 15
IDBP-535663 protocadherin 15
IDBP-534609 protocadherin 15
IDBP-532082 protocadherin 15
IDBP-534975 protocadherin 15
IDBP-537224 protocadherin 15
IDBP-710854
IDBP-534339 protocadherin 15
IDBP-532034 protocadherin 15
IDBP-535152 protocadherin 15
IDBP-532354 protocadherin 15
IDBP-540671 protocadherin 15
IDBP-539030 protocadherin 15
IDBP-710592
IDBP-714423
IDBP-711332
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000150275:
This gene is a member of the cadherin superfamily. Family members encode integral membrane proteins that mediate calcium-dependent cell-cell adhesion. It plays an essential role in maintenance of normal retinal and cochlear function. Mutations in this gene result in hearing loss and Usher Syndrome Type IF (USH1F). Extensive alternative splicing resulting in multiple isoforms has been observed in the mouse ortholog. Similar alternatively spliced transcripts are inferred to occur in human, and additional variants are likely to occur. [provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10: 73099342-74646314
Strand Forward strand
Band B5.3
Transcripts
ENSMUST00000092420  ENSMUSP00000090076
ENSMUST00000064562  ENSMUSP00000068561
ENSMUST00000105429  ENSMUSP00000101069
ENSMUST00000105426  ENSMUSP00000101066
ENSMUST00000105424  ENSMUSP00000101064
ENSMUST00000123398 
ENSMUST00000148572 
ENSMUST00000156999 
ENSMUST00000146682  ENSMUSP00000134863
ENSMUST00000136096  ENSMUSP00000121534
ENSMUST00000124046  ENSMUSP00000121130
ENSMUST00000131724  ENSMUSP00000122466
ENSMUST00000152655  ENSMUSP00000118201
ENSMUST00000149977  ENSMUSP00000118833
ENSMUST00000151116  ENSMUSP00000119662
ENSMUST00000147189  ENSMUSP00000122940
ENSMUST00000126920  ENSMUSP00000121939
ENSMUST00000131321  ENSMUSP00000122911
ENSMUST00000129404  ENSMUSP00000117731
ENSMUST00000155701  ENSMUSP00000135495
ENSMUST00000152819  ENSMUSP00000123647
ENSMUST00000125517  ENSMUSP00000115399
ENSMUST00000125055  ENSMUSP00000114326
ENSMUST00000125006  ENSMUSP00000120056
ENSMUST00000134009  ENSMUSP00000120618
ENSMUST00000147455 
ENSMUST00000139106 
ENSMUST00000128843 
ENSMUST00000144302  ENSMUSP00000122606
ENSMUST00000127928 
ENSMUST00000177420  ENSMUSP00000135849
ENSMUST00000177107  ENSMUSP00000135501
ENSMUST00000177128  ENSMUSP00000135888
Interactions
Number of Interactions   This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein‑Protein  4
[view]
Protein‑DNA 0
Protein‑RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
 
Gene Ontology
Accession GO Term
Molecular Function
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
GO:0001964 startle response
GO:0002009 morphogenesis of an epithelium
GO:0007015 actin filament organization
GO:0007156 homophilic cell adhesion
GO:0007601 visual perception
GO:0007605 sensory perception of sound
GO:0007626 locomotory behavior
GO:0007628 adult walking behavior
GO:0035058 nonmotile primary cilium assembly
GO:0035264 multicellular organism growth
GO:0042491 auditory receptor cell differentiation
GO:0048839 inner ear development
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound
GO:0050973 detection of mechanical stimulus involved in equilibrioception
GO:0060013 righting reflex
GO:0060088 auditory receptor cell stereocilium organization
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral to membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID Gene Order Method Confidence Comments
ENSG00000150275 Ortholuge Non-SSD Ortholog Possible paralog/unusual divergence/ gene prediction error
ENSBTAG00000045905 Not yet available Ortholuge Non-SSD Ortholog Possible paralog/unusual divergence/ gene prediction error
Pathways
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID BIOCARTA
PID NCI
Cross-References
SwissProt
TrEMBL D3YTL2 D6RCH0 E9Q159 E9Q7D7 E9Q7R2 F6KJX4 F6KKG6 F6R5Z7 F6RBV2 F6WUN7 F6Y0A5 F6YP25 F7ASH0 F7D5J8 F7DFU0 F8VQ61 H3BKS0 Q0ZM15 Q0ZM16 Q0ZM18 Q0ZM21 Q0ZM22 Q0ZM23 Q0ZM24 Q0ZM25 Q3UTS7
UniProt Splice Variant
Entrez Gene 11994 
UniGene Mm.338933 Mm.408656 Mm.479473
RefSeq NM_001142735  NM_001142736  NM_001142737  NM_001142738  NM_001142739  NM_001142740  NM_001142741  NM_001142742  NM_001142743  NM_001142746  NM_001142747  NM_001142748  NM_001142760  NM_023115 
OMIM
CCDS CCDS35934  CCDS48594  CCDS48595  CCDS56711  CCDS56712  CCDS56713  CCDS56714  CCDS56715  CCDS56716  CCDS56717  CCDS56718  CCDS56719  CCDS56720  CCDS56721 
HPRD
IMGT
MGI ID MGI:1891428 
MGI Symbol Pcdh15
EMBL AC108392 AC119894 AC121142 AC121602 AC121832 AC123032 AC123809 AC144802 AC147721 AC153858 AC158800 AC159477 AC186813 AC188091 AK139154 CAAA01110489 DQ354408 DQ354409 DQ354410 DQ354411 DQ354412 DQ354415 DQ354416 DQ354417 DQ354418 HQ404375 HQ420254
GenPept ABC79271  ABC79272  ABC79273  ABC79274  ABC79275  ABC79278  ABC79279  ABC79280  ABC79281  ADP09331  ADT91308  BAE23903 
ImmGen Pcdh15 (murine) 
RNA Seq Atlas 11994