Mus musculus Gene: Galc | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-162136.6 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | Galc | ||||||
Gene Name | galactosylceramidase | ||||||
Synonyms | 2310068B06Rik; A930008M05Rik; AW212969; AW413532; Gacy; twi; twitcher | ||||||
Species | Mus musculus | ||||||
Ensembl Gene | ENSMUSG00000021003 | ||||||
Encoded Proteins |
galactosylceramidase
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Protein Structure |
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Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000054983:
This gene encodes a lysosomal protein which hydrolyzes the galactose ester bonds of galactosylceramide, galactosylsphingosine, lactosylceramide, and monogalactosyldiglyceride. Mutations in this gene have been associated with Krabbe disease, also known as globoid cell leukodystrophy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 12:98202304-98259459 | ||||||
Strand | Reverse strand | ||||||
Band | E | ||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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Pathways | |||||||
NETPATH | |||||||
REACTOME |
Glycosphingolipid metabolism pathway
Metabolism pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
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KEGG |
Sphingolipid metabolism pathway
Lysosome pathway
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INOH | |||||||
PID NCI | |||||||
Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
Glycosphingolipid metabolism pathway
Sphingolipid metabolism pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
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KEGG |
Sphingolipid metabolism pathway
Lysosome pathway
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INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | P54818 | ||||||
TrEMBL | |||||||
UniProt Splice Variant | |||||||
Entrez Gene | 14420 | ||||||
UniGene | |||||||
RefSeq | NM_008079 | ||||||
OMIM | |||||||
CCDS | CCDS36517 | ||||||
HPRD | |||||||
IMGT | |||||||
MGI ID | MGI:95636 | ||||||
MGI Symbol | Galc | ||||||
EMBL | AF003870 AF003871 AF003872 AF003873 AF003874 AF003875 AF003876 AF003877 AF003878 AF003879 AF003880 AF003881 AF003882 AF003883 AF003884 AF003885 AF003886 AK154760 BC086671 CH466549 D38557 | ||||||
GenPept | AAB71823 AAH86671 BAA07560 BAE32809 EDL18937 | ||||||
RNA Seq Atlas | 14420 | ||||||