Mus musculus Gene: Slc7a8
Summary
InnateDB Gene IDBG-162168.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc7a8
Gene Name solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
Synonyms AA408822; LAT2
Species Mus musculus
Ensembl Gene ENSMUSG00000022180
Encoded Proteins
solute carrier family 7 (cationic amino acid transporter, y+ system), member 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000092068:
Gene Information
Type Protein coding
Genomic Location Chromosome 14:54722216-54781886
Strand Reverse strand
Band C2
Transcripts
ENSMUST00000022787 ENSMUSP00000022787
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005275 amine transmembrane transporter activity
GO:0005515 protein binding
GO:0015101 organic cation transmembrane transporter activity
GO:0015171 amino acid transmembrane transporter activity
GO:0015179 L-amino acid transmembrane transporter activity
GO:0019534 toxin transporter activity
Biological Process
GO:0003333 amino acid transmembrane transport
GO:0006810 transport
GO:0006865 amino acid transport
GO:0015695 organic cation transport
GO:0015807 L-amino acid transport
GO:0015837 amine transport
GO:0055085 transmembrane transport
GO:1901998 toxin transport
GO:1902475 L-alpha-amino acid transmembrane transport
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Hemostasis pathway
SLC-mediated transmembrane transport pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Cell surface interactions at the vascular wall pathway
Basigin interactions pathway
Transmembrane transport of small molecules pathway
Amino acid transport across the plasma membrane pathway
KEGG
Protein digestion and absorption pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Basigin interactions pathway
Cell surface interactions at the vascular wall pathway
Amino acid transport across the plasma membrane pathway
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
Transmembrane transport of small molecules pathway
SLC-mediated transmembrane transport pathway
Hemostasis pathway
KEGG
Protein digestion and absorption pathway
INOH
PID NCI
Cross-References
SwissProt Q9QXW9
TrEMBL
UniProt Splice Variant
Entrez Gene 50934
UniGene Mm.276831
RefSeq NM_016972 XM_006519250
OMIM
CCDS CCDS27101
HPRD
IMGT
MGI ID MGI:1355323
MGI Symbol Slc7a8
EMBL AF171668 BC059004 Y19022
GenPept AAF20380 AAH59004 CAB69072
RNA Seq Atlas 50934