Mus musculus Gene: P2ry4
Summary
InnateDB Gene IDBG-162171.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol P2ry4
Gene Name pyrimidinergic receptor P2Y, G-protein coupled, 4
Synonyms P2Y4; P2Y4R
Species Mus musculus
Ensembl Gene ENSMUSG00000044359
Encoded Proteins
pyrimidinergic receptor P2Y, G-protein coupled, 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186912:
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:100590154-100594869
Strand Reverse strand
Band C3
Transcripts
ENSMUST00000053373 ENSMUSP00000055869
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
GO:0005524 ATP binding
GO:0019103 pyrimidine nucleotide binding
GO:0045028 G-protein coupled purinergic nucleotide receptor activity
GO:0045030 UTP-activated nucleotide receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0030321 transepithelial chloride transport
GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway
Cellular Component
GO:0016021 integral component of membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
P2Y receptors pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Nucleotide-like (purinergic) receptors pathway
GPCR ligand binding pathway
G alpha (i) signalling events pathway
Signal Transduction pathway
KEGG
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (i) signalling events pathway
P2Y receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
Nucleotide-like (purinergic) receptors pathway
KEGG
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt Q9JJS7
TrEMBL Q0VBT7
UniProt Splice Variant
Entrez Gene 57385
UniGene Mm.117118
RefSeq NM_020621 XM_006528175 XM_006528176 XM_006528177 XM_006528178 XM_006528179
OMIM
CCDS CCDS30303
HPRD
IMGT
MGI ID MGI:1926594
MGI Symbol P2ry4
EMBL AJ277752 AK076364 BC119206 BC120511 CH466564
GenPept AAI19207 AAI20512 BAC36314 CAB91043 EDL14179
RNA Seq Atlas 57385