InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: P2ry4

Summary

InnateDB Protein

IDBP-162173.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

P2ry4

Protein Name

pyrimidinergic receptor P2Y, G-protein coupled, 4

Synonyms

P2Y4; P2Y4R;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000055869

InnateDB Gene

IDBG-162171 (P2ry4)

Protein Structure

UniProt Annotation

Function

Receptor for ATP and UTP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system.

Subcellular Localization

Cell membrane; Multi-pass membrane protein.

Disease Associations

Tissue Specificity

Expressed in the liver, intestine, stomach, bladder and lung.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004930	G-protein coupled receptor activity
GO:0005524	ATP binding
GO:0019103	pyrimidine nucleotide binding
GO:0045028	G-protein coupled purinergic nucleotide receptor activity
GO:0045030	UTP-activated nucleotide receptor activity

Biological Process

GO:0007186	G-protein coupled receptor signaling pathway
GO:0030321	transepithelial chloride transport
GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway