Version 5.4
| Mus musculus Gene: Dyrk1b | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-162371.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | Dyrk1b | ||||||||||||||||||
| Gene Name | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b | ||||||||||||||||||
| Synonyms | Mirk | ||||||||||||||||||
| Species | Mus musculus | ||||||||||||||||||
| Ensembl Gene | ENSMUSG00000002409 | ||||||||||||||||||
| Encoded Proteins |
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105204:
DYRK1B is a member of the DYRK family of protein kinases. DYRK1B contains a bipartite nuclear localization signal and is found mainly in muscle and testis. The protein is proposed to be involved in the regulation of nuclear functions. Three isoforms of DYRK1B have been identified differing in the presence of two alternatively spliced exons within the catalytic domain. [provided by RefSeq, Jul 2008] This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdominal obesity-metabolic syndrome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 7:28179469-28187294 | ||||||||||||||||||
| Strand | Forward strand | ||||||||||||||||||
| Band | A3 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Homo sapiens
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathway Predictions based on Human Orthology Data | |||||||||||||||||||
| NETPATH |
EGFR1 pathway
TCR pathway
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| REACTOME | |||||||||||||||||||
| KEGG | |||||||||||||||||||
| INOH | |||||||||||||||||||
| PID NCI | |||||||||||||||||||
| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| UniGene | Mm.410598 Mm.57249 | ||||||||||||||||||
| RefSeq | NM_001037957 NM_001271370 NM_010092 XM_006539527 | ||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS21037 CCDS57532 | ||||||||||||||||||
| HPRD | |||||||||||||||||||
| IMGT | |||||||||||||||||||
| MGI ID | |||||||||||||||||||
| MGI Symbol | |||||||||||||||||||
| EMBL | |||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||