Mus musculus Gene: Gdf1
Summary
InnateDB Gene IDBG-162564.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gdf1
Gene Name growth differentiation factor 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000055694
Encoded Proteins
growth differentiation factor 1
LAG1 homolog, ceramide synthase 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site that is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This protein is involved in the establishment of left-right asymmetry in early embryogenesis and in neural development in later embryogenesis. This protein is transcribed from a monocistronic mRNA early in development, and from a bicistronic mRNA in later stages that also encodes the LAG1 homolog, ceramide synthase 1 gene. [provided by RefSeq, Jul 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:70329817-70331587
Strand Forward strand
Band B3.3
Transcripts
ENSMUST00000046516 ENSMUSP00000045892
ENSMUST00000165819 ENSMUSP00000128325
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0008083 growth factor activity
Biological Process
GO:0040007 growth
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Signaling by NODAL pathway
Developmental Biology pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Signaling by NODAL pathway
Developmental Biology pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P20863
TrEMBL
UniProt Splice Variant
Entrez Gene 14559
UniGene Mm.258280 Mm.481151 Mm.481331
RefSeq NM_008107 NM_001163282 NM_138647
OMIM
CCDS CCDS52571 CCDS52570
HPRD
IMGT
MGI ID MGI:95683
MGI Symbol Gdf1
EMBL BC079555 M57639 M62301
GenPept AAA37674 AAA37676 AAH79555
RNA Seq Atlas 14559