Version 5.4
Mus musculus Gene: Isyna1
Summary
InnateDB Gene IDBG-163508.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Isyna1
Gene Name myo-inositol 1-phosphate synthase A1
Synonyms 1300017C10Rik; AU018670
Species Mus musculus
Ensembl Gene ENSMUSG00000019139
Encoded Proteins
IDBP-163510
myo-inositol 1-phosphate synthase A1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000105655:
This gene encodes an inositol-3-phosphate synthase enzyme. The encoded protein plays a critical role in the myo-inositol biosynthesis pathway by catalyzing the rate-limiting conversion of glucose 6-phosphate to myoinositol 1-phosphate. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the short arm of chromosome 4. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:70594481-70597288
Strand Forward strand
Band B3.3
Transcripts
ENSMUST00000019283 ENSMUSP00000019283
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0004512 inositol-3-phosphate synthase activity
Biological Process
GO:0006021 inositol biosynthetic process
GO:0008150 biological_process
GO:0008654 phospholipid biosynthetic process
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000105655
View Gene Order
ENSBTAG00000017482
Not yet available
Pathways
NETPATH
REACTOME
REACT_196478
Synthesis of IP2, IP, and Ins in the cytosol pathway
REACT_188937
Metabolism pathway
REACT_196476
Inositol phosphate metabolism pathway
KEGG
mmu00562
Inositol phosphate metabolism pathway
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150352
Synthesis of IP2, IP, and Ins in the cytosol pathway
REACT_150154
Inositol phosphate metabolism pathway
REACT_111217
Metabolism pathway
REACT_219139
Metabolism pathway
REACT_212018
Synthesis of IP2, IP, and Ins in the cytosol pathway
REACT_211106
Inositol phosphate metabolism pathway
KEGG
hsa00562
Inositol phosphate metabolism pathway
INOH
INOH website
Inositol phosphate metabolism pathway
PID NCI
Cross-References
SwissProt Q9JHU9
TrEMBL
UniProt Splice Variant
Entrez Gene 71780
UniGene
RefSeq NM_023627
OMIM
CCDS CCDS22373
HPRD
IMGT
MGI ID MGI:1919030
MGI Symbol Isyna1
EMBL AF288525 AK005029 AK079323 BC003458
GenPept AAF90201 AAH03458 BAB23756 BAC37607
RNA Seq Atlas 71780

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca