Version 5.4
Mus musculus Gene: Timm8b
Summary
InnateDB Gene IDBG-163586.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Timm8b
Gene Name translocase of inner mitochondrial membrane 8B
Synonyms Tim8b
Species Mus musculus
Ensembl Gene ENSMUSG00000039016
Encoded Proteins
IDBP-163588
translocase of inner mitochondrial membrane 8 homolog b (yeast)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000150779:
This gene encodes a member of a well-conserved family of proteins with similarity to yeast Tim mitochondrial import proteins. This gene is encoded by a nuclear gene and is transported into the intermembrane space of the mitochondrion. When formed into complexes, these proteins guide membrane-spanning proteins across the mitochondrial intermembrane space before they are added into the mitochondrial inner membrane. This gene is adjacent to succinate dehydrogenase, subunit D (SDHD), in which mutations have been found in affected members of families with hereditary paraganglioma.[provided by RefSeq, Aug 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:50603901-50605320
Strand Forward strand
Band A5.3
Transcripts
ENSMUST00000044051 ENSMUSP00000039335
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0046872 metal ion binding
Biological Process
GO:0015031 protein transport
Cellular Component
GO:0005615 extracellular space
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000150779
View Gene Order
ENSBTAG00000002000
Not yet available
Pathways
NETPATH
REACTOME
REACT_247926
Metabolism of proteins pathway
REACT_199101
Mitochondrial protein import pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_118595
Mitochondrial protein import pathway
REACT_17015
Metabolism of proteins pathway
REACT_215731
Mitochondrial protein import pathway
REACT_213782
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt P62077
TrEMBL
UniProt Splice Variant
Entrez Gene 30057
UniGene
RefSeq NM_013897
OMIM
CCDS CCDS40624
HPRD
IMGT
MGI ID MGI:1353424
MGI Symbol Timm8b
EMBL AF196314 AK003382 AK004190 AK012925 AK018718 AK019422 AK169258 BC029239
GenPept AAF13228 AAH29239 BAB22753 BAB23213 BAB28552 BAB31364 BAB31713 BAE41021
RNA Seq Atlas 30057

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca