Version 5.4
Mus musculus Gene: Pttg1
Summary
InnateDB Gene IDBG-163985.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pttg1
Gene Name pituitary tumor-transforming gene 1
Synonyms AW555095; C87862; Pttg; Pttg3
Species Mus musculus
Ensembl Gene ENSMUSG00000020415
Encoded Proteins
IDBP-163987
pituitary tumor-transforming gene 1
IDBP-163989
pituitary tumor-transforming gene 1
IDBP-163991
pituitary tumor-transforming gene 1
IDBP-400837
pituitary tumor-transforming gene 1
IDBP-400836
pituitary tumor-transforming gene 1
IDBP-400834
pituitary tumor-transforming gene 1
IDBP-534236
pituitary tumor-transforming gene 1
IDBP-539250
pituitary tumor-transforming gene 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:43420250-43426251
Strand Reverse strand
Band B1.1
Transcripts
ENSMUST00000020685 ENSMUSP00000020685
ENSMUST00000101340 ENSMUSP00000098894
ENSMUST00000020687 ENSMUSP00000020687
ENSMUST00000118368 ENSMUSP00000112834
ENSMUST00000121638 ENSMUSP00000112815
ENSMUST00000117446 ENSMUSP00000112841
ENSMUST00000140434 ENSMUSP00000122019
ENSMUST00000152115 ENSMUSP00000119554
ENSMUST00000150726
ENSMUST00000148130
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004869 cysteine-type endopeptidase inhibitor activity
GO:0017124 SH3 domain binding
GO:0031072 heat shock protein binding
GO:0043022 ribosome binding
Biological Process
GO:0001558 regulation of cell growth
GO:0006281 DNA repair
GO:0007059 chromosome segregation
GO:0007067 mitotic nuclear division
GO:0008285 negative regulation of cell proliferation
GO:0009987 cellular process
GO:0010951 negative regulation of endopeptidase activity
GO:0045143 homologous chromosome segregation
GO:0051276 chromosome organization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
REACT_249770
Cell Cycle, Mitotic pathway
REACT_222875
APC/C:Cdc20 mediated degradation of mitotic proteins pathway
REACT_207679
Separation of Sister Chromatids pathway
REACT_222604
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins pathway
REACT_188804
Cell Cycle pathway
REACT_244364
APC/C-mediated degradation of cell cycle proteins pathway
REACT_241408
M Phase pathway
REACT_226135
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 pathway
REACT_254995
Regulation of mitotic cell cycle pathway
REACT_219897
APC/C:Cdc20 mediated degradation of Securin pathway
REACT_199403
Mitotic Metaphase and Anaphase pathway
REACT_202512
Mitotic Anaphase pathway
KEGG
mmu04110
Cell cycle pathway
mmu04114
Oocyte meiosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.473416 Mm.6856
RefSeq NM_001131054 NM_013917 XM_006533515 XM_006533516
OMIM
CCDS CCDS24556 CCDS48771
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca