Version 5.4
Homo sapiens Gene: DPPA3
Summary
InnateDB Gene IDBG-16436.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DPPA3
Gene Name developmental pluripotency associated 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000187569
Encoded Proteins
IDBP-16438
developmental pluripotency associated 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance of cell pluripotentiality. In humans, related intronless loci are located on chromosomes 14 and X. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:7711454-7717559
Strand Forward strand
Band p13.31
Transcripts
ENST00000345088 ENSP00000339250
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0035064 methylated histone binding
Biological Process
GO:0016568 chromatin modification
GO:0040016 embryonic cleavage
GO:0044726 protection of DNA demethylation of female pronucleus
GO:1901536 negative regulation of DNA demethylation
GO:2000653 regulation of genetic imprinting
Cellular Component
GO:0001939 female pronucleus
GO:0001940 male pronucleus
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
No orthologs found for this gene
Cross-References
SwissProt Q6W0C5
TrEMBL
UniProt Splice Variant
Entrez Gene 359787
UniGene Hs.131358
RefSeq NM_199286
HUGO HGNC:19199
OMIM 608408
CCDS CCDS8582
HPRD
IMGT
EMBL AY230136 AY317075 BC062480 BC125145
GenPept AAH62480 AAI25146 AAO39708 AAQ84110
RNA Seq Atlas 101060236 359787

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca