Version 5.4
Mus musculus Gene: Pygo2
Summary
InnateDB Gene IDBG-164590.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Pygo2
Gene Name pygopus 2
Synonyms 1190004M21Rik
Species Mus musculus
Ensembl Gene ENSMUSG00000047824
Encoded Proteins
IDBP-164592
pygopus 2
IDBP-266725
pygopus 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163348:
Gene Information
Type Protein coding
Genomic Location Chromosome 3:89430214-89435128
Strand Forward strand
Band F1
Transcripts
ENSMUST00000060061 ENSMUSP00000053672
ENSMUST00000107413 ENSMUSP00000103036
ENSMUST00000136573
ENSMUST00000146037
ENSMUST00000133680
ENSMUST00000125830
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003682 chromatin binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0035034 histone acetyltransferase regulator activity
GO:0042393 histone binding
Biological Process
GO:0001701 in utero embryonic development
GO:0001822 kidney development
GO:0002088 lens development in camera-type eye
GO:0007286 spermatid development
GO:0007289 spermatid nucleus differentiation
GO:0007420 brain development
GO:0009791 post-embryonic development
GO:0016055 Wnt signaling pathway
GO:0030879 mammary gland development
GO:0033599 regulation of mammary gland epithelial cell proliferation
GO:0035065 regulation of histone acetylation
GO:0035563 positive regulation of chromatin binding
GO:0048589 developmental growth
GO:0051569 regulation of histone H3-K4 methylation
GO:0060021 palate development
GO:0060070 canonical Wnt signaling pathway
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163348
View Gene Order
ENSBTAG00000004331
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_228096
misspliced LRP5 mutants have enhanced beta-catenin-dependent signaling pathway
REACT_228331
Signaling by WNT in cancer pathway
REACT_11045
Signaling by Wnt pathway
REACT_200731
deactivation of the beta-catenin transactivating complex pathway
REACT_111102
Signal Transduction pathway
REACT_200777
TCF dependent signaling in response to WNT pathway
REACT_228188
RNF mutants show enhanced WNT signaling and proliferation pathway
REACT_200753
formation of the beta-catenin:TCF transactivating complex pathway
REACT_228279
XAV939 inhibits tankyrase, stabilizing AXIN pathway
REACT_116125
Disease pathway
KEGG
INOH
INOH website
Wnt signaling pathway pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.22521 Mm.474922
RefSeq NM_026869 XM_006502003 XM_006502004 XM_006502005 XM_006502006
OMIM
CCDS CCDS38494
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca