InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ndufa8

Summary

InnateDB Gene

IDBG-164898.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndufa8

Gene Name

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8

Synonyms

0610033L03Rik; AW261656

Species

Mus musculus

Ensembl Gene

ENSMUSG00000026895

Encoded Proteins

IDBP-164900

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119421:
The protein encoded by this gene belongs to the complex I 19 kDA subunit family. Mammalian complex I is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It plays an important role in transfering electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:36036326-36049406

Strand

Reverse strand

Band

Transcripts

ENSMUST00000070112

ENSMUSP00000065352

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	20 [view]
Protein-Protein	20 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0032403	protein complex binding

Biological Process

GO:0008150	biological_process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005747	mitochondrial respiratory chain complex I
GO:0005758	mitochondrial intermembrane space