InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ndufa8

Summary

InnateDB Protein

IDBP-164900.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndufa8

Protein Name

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8

Synonyms

0610033L03Rik; AW261656;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000065352

InnateDB Gene

IDBG-164898 (Ndufa8)

Protein Structure

UniProt Annotation

Function

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.

Subcellular Localization

Mitochondrion {ECO:0000250}. Mitochondrion intermembrane space {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	20 [view]
Protein-Protein	20 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0032403	protein complex binding

Biological Process

GO:0008150	biological_process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005747	mitochondrial respiratory chain complex I
GO:0005758	mitochondrial intermembrane space