InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Nr2f6

Summary

InnateDB Gene

IDBG-165392.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Nr2f6

Gene Name

nuclear receptor subfamily 2, group F, member 6

Synonyms

AV090102; COUP-TF3; EAR2; Erbal2

Species

Mus musculus

Ensembl Gene

ENSMUSG00000002393

Encoded Proteins

IDBP-165394

nuclear receptor subfamily 2, group F, member 6

IDBP-536163

nuclear receptor subfamily 2, group F, member 6

IDBP-531611

nuclear receptor subfamily 2, group F, member 6

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000160113:

Gene Information

Type

Protein coding

Genomic Location

Chromosome 8:71374123-71381960

Strand

Reverse strand

Band

B3.3

Transcripts

ENSMUST00000002466	ENSMUSP00000002466
ENSMUST00000132630
ENSMUST00000137734
ENSMUST00000155463
ENSMUST00000156270
ENSMUST00000124732	ENSMUSP00000116498
ENSMUST00000127443
ENSMUST00000137058	ENSMUSP00000121648

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	22 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001227	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003707	steroid hormone receptor activity
GO:0004879	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0030522	intracellular receptor signaling pathway
GO:0043153	entrainment of circadian clock by photoperiod
GO:0043401	steroid hormone mediated signaling pathway
GO:0048666	neuron development
GO:0050965	detection of temperature stimulus involved in sensory perception of pain

Cellular Component

GO:0005634

nucleus

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000160113

View Gene Order

ENSBTAG00000011136

Not yet available

Pathways

NETPATH

REACTOME

REACT_234105

Nuclear Receptor transcription pathway pathway

REACT_233572

Gene Expression pathway

REACT_206529

Generic Transcription Pathway pathway

KEGG

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

REACT_15525

Nuclear Receptor transcription pathway pathway

REACT_12627

Generic Transcription Pathway pathway

REACT_71

Gene Expression pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

P43136

TrEMBL

UniProt Splice Variant

Entrez Gene

13864

UniGene

Mm.28989

RefSeq

NM_010150

OMIM

CCDS

CCDS22392

HPRD

IMGT

MGI ID

MGI:1352453

MGI Symbol

Nr2f6

EMBL

AK131941 AK171552 BC008138 CH466569 L25674 X76654

GenPept

AAA37532 AAH08138 BAE20887 BAE42523 CAA54097 EDL28911

RNA Seq Atlas

13864