InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Gene: NR2F6

Summary

InnateDB Gene

IDBG-36169.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NR2F6

Gene Name

nuclear receptor subfamily 2, group F, member 6

Synonyms

EAR-2; EAR2; ERBAL2

Species

Homo sapiens

Ensembl Gene

ENSG00000160113

Encoded Proteins

IDBP-36171

nuclear receptor subfamily 2, group F, member 6

IDBP-762070

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:17231883-17245940

Strand

Reverse strand

Band

p13.11

Transcripts

ENST00000291442	ENSP00000291442
ENST00000596878	ENSP00000471686

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	19 [view]
Protein-Protein	17 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001227	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003707	steroid hormone receptor activity
GO:0004879	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004887	thyroid hormone receptor activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006367	transcription initiation from RNA polymerase II promoter
GO:0007165	signal transduction
GO:0010467	gene expression
GO:0030522	intracellular receptor signaling pathway
GO:0043153	entrainment of circadian clock by photoperiod
GO:0043401	steroid hormone mediated signaling pathway
GO:0048666	neuron development
GO:0050965	detection of temperature stimulus involved in sensory perception of pain

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm

Orthologs

Species

Mus musculus

Bos taurus

Gene ID

Gene Order

ENSMUSG00000002393

View Gene Order

ENSBTAG00000011136

Not yet available

Pathways

NETPATH

REACTOME

REACT_15525

Nuclear Receptor transcription pathway pathway

REACT_12627

Generic Transcription Pathway pathway

REACT_71

Gene Expression pathway

KEGG

INOH

PID NCI

Cross-References

SwissProt

P10588

TrEMBL

F1D8R3 M0R175 M0R384

UniProt Splice Variant

Entrez Gene

2063

UniGene

Hs.466148

RefSeq

NM_005234

HUGO

HGNC:7977

OMIM

132880

CCDS

CCDS12352

HPRD

IMGT

EMBL

AC010646 AC104522 AK314961 BC002669 BC063018 BC084544 CH471106 HQ692851 X12794

GenPept

AAH02669 AAH63018 AAH84544 ADZ17362 BAG37465 CAA31282 EAW84580

RNA Seq Atlas

2063