InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Ndufs6

Summary

InnateDB Gene

IDBG-165540.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ndufs6

Gene Name

NADH dehydrogenase (ubiquinone) Fe-S protein 6

Synonyms

Species

Mus musculus

Ensembl Gene

ENSMUSG00000021606

Encoded Proteins

IDBP-165542

NADH dehydrogenase (ubiquinone) Fe-S protein 6

IDBP-534769

NADH dehydrogenase (ubiquinone) Fe-S protein 6

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000145494:
This gene encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.[provided by RefSeq, Oct 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 13:73319874-73328542

Strand

Reverse strand

Band

Transcripts

ENSMUST00000022097	ENSMUSP00000022097
ENSMUST00000147407	ENSMUSP00000119457

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	25 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function

Biological Process

GO:0006631	fatty acid metabolic process
GO:0006936	muscle contraction
GO:0010259	multicellular organismal aging
GO:0022904	respiratory electron transport chain
GO:0035264	multicellular organism growth
GO:0061458	reproductive system development
GO:0070584	mitochondrion morphogenesis
GO:0072358	cardiovascular system development